ChemInform Abstract: Asymmetric Total Syntheses of Hydroxylated Piperidine Alkaloids via the Intramolecular Reaction of γ‐Aminoallylstannane with Aldehyde.

Abstract

Asymmetric Total Syntheses of Hydroxylated Piperidine Alkaloids via the Intramolecular Reaction of γ-Aminoallylstannane with Aldehyde.-The key step in the synthesis of (+)-desoxoprosopinine (VIII) and (-)-desoxoprosophylline (IX) is the cyclization of the aminoallylstannane (V). -(KADOTA, I.; KAWADA, M.; MURAMATSU, Y.; YAMAMOTO, Y.; Tetrahedron: Asymmetry 8 (1997) 23, 3887-3893; Dep. Chem., Fac. Sci., Tohoku Univ., Aoba, Sendai 980, Japan; EN)