Abstract:Choline Chloride/Urea Ionic Liquid Catalyzed a Convenient One-Pot Synthesis of Indole-3-propanamide Derivatives. -A versatile and general method for the synthesis of indole-3-propanamides (V) is development using the three-component reaction of indole (I) with Meldrum's acid and aldehydes and subsequent reaction of the Meldrum's adduct formed with amines. Treatment of the Meldrum's adducts with water affords exclusively the corresponding propanoic acids (VII). -(SIDDALINGAMURTHY, E.; MAHADEVAN*, K. M.; KUMAR, … Show more
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