ChemInform Abstract: ClickEnam. Part 1. Synthesis of Novel 1,4‐Disubstituted‐[1,2,3]‐triazole‐derived β‐Aminovinyl Trifluoromethylated Ketones and Their Copper(II) Complexes.

Abstract

triazole-derived β-Aminovinyl Trifluoromethylated Ketones and Their Copper(II) Complexes. -The synthesized compounds are screened as potential antifungal agents. Aminovinyl ketones (IIIa) and (IIIb) show weak in vitro activities against P. falciparum strains. -(CHOPIN, N.; DECAMPS, S.; GOUGER, A.; MEDEBIELLE*, M.; PICOT, S.; BIENVENU, A.-L.; PILET, G.; J. Fluorine Chem. 132 (2011) 10, 850-857, http://dx.