ChemInform Abstract: Cyclic α‐Amino Acids as Precursors for Synthesis of 2‐Amino‐3‐hetarylpyrrolin‐4‐ones and Their Spiro Derivatives.

Abstract

A facile route for the synthesis of hetarylpyrrolinones and corresponding spiro‐derivatives based on the reaction of N‐protected amino acids (I) with benzimidazolylacetonitriles (II) or thiazole analogues is developed.