ChemInform Abstract: Development of an Azanoradamantane‐Type Nitroxyl Radical Catalyst for Class‐Selective Oxidation of Alcohols.

Abstract

Development of an Azanoradamantane-Type Nitroxyl Radical Catalyst for Class--Selective Oxidation of Alcohols. -The title catalyst is prepared on gram scale in an eight-step sequence and affords superior results to TEMPO and its 1-methylazaadamantane analogue, not only for the class-selective oxidation of primary alcohols to aldehydes in the presence of a secondary alcohol, but also for the selective one-pot oxidation to carboxylic acids as well as for oxidative lactonization. -(DOI, R.; SHIBUYA, M.; MURAYAMA, T.; YAMAMOTO, Y.; IWABUCHI*, Y.; J. Org. Chem. 80 (2015) 1, 401-413, http://dx.