ChemInform Abstract: Diarylprolinol Silyl Ether Catalyzed Asymmetric Friedel—Crafts Alkylation of Indoles with α,β‐Unsaturated Aldehydes: Enhanced Enantioselectivity and Mechanistic Investigations.

Abstract

This improved method offers substantial advantages over traditional approaches such as avoiding the use of acids or bases and the high level of stereoselectivity.