ChemInform Abstract: Direct Conversion of 1‐(2‐Bromobenzoyl)isoquinolines to Dibenzo[de,g]quinolin‐7‐ones via Reductive Photocyclization.

Abstract

Direct Conversion of 1-(2-Bromobenzoyl)isoquinolines to Dibenzo[de,g]quinolin--7-ones via Reductive Photocyclization. -A convenient and new one-pot method for the synthesis of tetracyclic alkaloids is presented via reductive photocyclization. The yields are enhanced when -O-Me is at the 5-or 7-position of the isoquinolyl ring or -CF3 at the 5-position of the phenyl group.