ChemInform Abstract: Efficient Kinetic Resolution of Racemic Amino Aldehydes by Oxidation with N‐Iodosuccinimide.

Abstract

Enantioselective syntheses O 0031 Efficient Kinetic Resolution of Racemic Amino Aldehydes by Oxidation with N-Iodosuccinimide. -The aldehydes are efficiently resolved by treatment with NIS and Cu(II)/(R,R)-Ph-box as catalyst in MeOH into optically active amino acid methyl esters and amino aldehyde dimethyl acetals. -(MINATO, D.; NAGASUE, Y.; DEMIZU, Y.; ONOMURA*, O.; Angew. Chem., Int. Ed. 47 (2008) 49, 9458-9461; Grad. Sch. Biomed. Sci., Nagasaki Univ., Nagasaki 852, Japan; Eng.) -Klein 14-025