ChemInform Abstract: Efficient ′One‐Pot′ Methodology for the Synthesis of Novel Tetrahydro‐β‐carboline, Tetrahydroisoquinoline and Tetrahydrothienopyridine Derivatives.

Abstract

Efficient 'One-Pot' Methodology for the Synthesis of Novel Tetrahydro-β-carboline, Tetrahydroisoquinoline and Tetrahydrothienopyridine Derivatives. -This simple and general method gives an efficient access to the title compounds via the Pictet-Spengler type cyclization. The obtained products are useful precursors for the synthesis of compounds with potential antitumoral activity. -(IONESCU, A.; CORNUT, D.; SORIANO, S.; GUISSART, C.; VAN ANTWERPEN, P.; JABIN*, I.; Tetrahedron Lett. 54 (2013) 45, 6087-6089, http://dx.doi.org/10.1016/j.tetlet.2013.08.135 ; Lab. Chim. Org., Univ. Libre Bruxelles, B-1050 Bruxelles, Belg.; Eng.) -Mais 11-175