ChemInform Abstract: Electrophilic Aromatic Substitution. Part 36. Protiodetritiation of Some Annelated meta‐Cyclophanes: Effect of Ring‐Buckling on Reactivity, and the First Example of Electrophilic Substitution Through a Hole.

Abstract

The partial rate factors of the protiodetritiation of (Ia) with trifluoroacetic acid at 70 °C increase when the size of the bridge decreases due to the loss of ground‐state aromaticity of the ring containing the alkyl chain.