ChemInform Abstract: ELLIPTICINE DERIVATIVES WITH AN AFFINITY TO THE ESTROGEN RECEPTOR. AN APPROACH TO DEVELOP INTERCALATING DRUGS WITH A SPECIFIC EFFECT ON THE HORMONE‐DEPENDENT BREAST CANCER
Abstract:Entsprechend dem Formelschema wird zunächst aus dem Benzophenon (Ia) die Schlüsselverbindung (IVa) dargestellt und, nach Einführung geeigneter Schutzgruppen, mit den Ellipticin‐Derivaten (Va) und (Vb) zu den Verbindungen (VI) umgesetzt.
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