NuH
Basic mediumNeutral medium Nu − Scheme 5.1 Different pathways for reaction of tetrafluoroethylene with nucleophiles.On reaction with basic nucleophiles, for example, organometallic species or alcoholates, substitution products are obtained [2]. With only mildly basic to neutral nucleophiles, such as phenolate-phenol mixtures, on the other hand, addition products predominate [3] (Scheme 5.2).