ChemInform Abstract: NEW METHOD FOR THE SYNTHESIS OF PHOSPHORYLATED FORMALS

Abstract

Phosphite wie (I) reagieren mit Diethoxymethylacetat (II) zu Phosphonaten wie (III).

Chemistry of Phosphorylated Formaldehyde Derivatives. Part I

“…It was reported that the reaction of trialkyl phosphites 58 with acetoxy(diethoxy)methane ( 61 ), which is more reactive derivative than orthoformate esters 54 [19,82], results in dialkyl (diethoxymethyl)phosphonates 62 (Scheme 10).…”

“…Alkyl alkyl(dialkoxymethyl)phosphinates 83 unsymmetrically substituted at the phosphorus atom were synthesized by the Arbuzov reaction of dialkyl (dialkoxymethyl)phosphonites 84 with alkyl iodides [82,84], for example see Scheme 16.…”