ChemInform Abstract: Nonenzymatic Kinetic Resolution of Racemic Alcohols Through an “ Induced Fit” Process.

Abstract

1997 stereochemistry stereochemistry (general, optical resolution) O 0030 -035Nonenzymatic Kinetic Resolution of Racemic Alcohols Through an " Induced Fit" Process.-A series of racemic alcohols such as (±)-(I) is resolved employing the nucleophilic catalyst NPCP, acting through an "induced fit" mechanism like natural enzymes despite its low molecular weight.-(KAWABATA, T.; NAGATO, M.; TAKASU, K.; FUJI, K.; J. Am. Chem. Soc.