ChemInform Abstract: Nucleophilic Addition to N‐Phosphinylimines by Rare‐Earth‐Metal Triflate/Trifluoroacetic Anhydride Activation.

Abstract

Addition reactions O 0060Nucleophilic Addition to N-Phosphinylimines by Rare-Earth-Metal Triflate/Trifluoroacetic Anhydride Activation. -Hydrated lanthanum triflate is shown to catalyze nucleophilic addition to N-phosphinylimine substrates in the presence of TFAA. Unexpectedly, trifluoroactamides (IV), (VII), or (IX) are obtained in a novel process which likely involves consecutive acylation/hydration of the N-phosphinylamine and subsequent nucleophilic addition. -(ONG, W. W.; BEELER, A. B.; KESAVAN, S.; PANEK, J. S.; PORCO*, J. A.