ChemInform Abstract: One‐Pot Synthesis and Cytotoxicity Studies of New Mannich Base Derivatives of Polyether Antibiotic—Lasalocid Acid.

Abstract

Acid. -7 Title compounds of type (IV) are prepared whereby, (IVb-c) show very good anticancer activity. -(HUCZYNSKI*, A.; RUTKOWSKI, J.; BOROWICZ, I.; WIETRZYK, J.; MAJ, E.; BRZEZINSKI, B.; Bioorg. Med. Chem. Lett. 23 (2013) 18, 5053-5056, http://dx.doi.org/10.1016/j.bmcl.2013.07.040 ; Fac. Chem., Adam Mickiewicz Univ., PL-60-780 Poznan, Pol.; Eng.) -M. Bohle 04-208