ChemInform Abstract: Parallel Kinetic Resolution of Racemic Aldehydes by Use of Asymmetric Horner—Wadsworth—Emmons Reactions.

Abstract

2000 stereochemistry stereochemistry (general, optical resolution) O 0030 -043Parallel Kinetic Resolution of Racemic Aldehydes by Use of Asymmetric Horner-Wadsworth-Emmons Reactions.-The parallel kinetic resolution allows efficient conversion of a racemic aldehyde to two different chiral products of high isomeric purity. This can be accomplished either by using two chiral phosphonate reagents containing different chiral auxiliaries or by using one (Z)-selective and one (E)-selective reagent bearing the same auxiliary. -(PEDERSEN, TORBEN M.; JENSEN, JAKOB F.; HUMBLE, RIKKE E.; REIN, TOBIAS; TANNER, DAVID; BODMANN,