ChemInform Abstract: Preparation and Evaluation of N‐Sulfinyl Dienophiles for Asymmetric Hetero‐Diels—Alder Reactions.

Abstract

Hetero-Diels-Alder Reactions. -Several N-sulfinyl dienophiles (I) are screened in Cu-or Zn-catalyzed asymmetric hetero-Diels-Alder reactions with cyclohexadiene in the presence of chiral bisoxazoline ligands. Derivative (Ia) appears to be a promising dienophile with respect to product yield and stereoselectivity (up to 97% e.e.). -(ENDESHAW, M. M.; HANSEN, L. K.; GAUTUN*, O. R.; J. Heterocycl. Chem. 45 (2008) 1, 149-154; Dep. Chem., Norw. Univ. Sci. Technol., N-7491 Trondheim, Norway; Eng.) -R. Staver 19-163