ChemInform Abstract: Selective Esterification of N‐Benzyl‐L‐aspartic Acid. Part 1. Some Modified Methods for the Preparation of N‐Benzylaspartic Anhydride Hydrobromide.

Abstract

ChemInform Abstract The most convenient route to the title anhydride (VI) is the one-pot reaction of N-benzylaspartic acid (V), derived from maleic anhydride (I), with 30% HBr in AcOH and Ac2O. (VI) is selectively esterified to afford the product (VII).