ChemInform Abstract: Straightforward Synthesis and Antioxidant Studies of Chalcogenoaziridines.

Abstract

Compound (IIIb) shows potential as an antioxidative agent.

Evaluation of Se-phenyl-thiazolidine-4-carboselenoate protective activity against oxidative and behavioral stress in the maniac model induced by ouabain in male rats

“…Evidence has been provided indicating that organoselenium compounds could be considered as potential antioxidant and neuroprotector compounds, besides their ability to prevent disease, which turns them a target for pharmacological studies [3,4,5,6,7,8]. 4 Selenium is an essential trace element nutritionally important to mammals, with physiological roles as a structural component of antioxidant enzymes involved in the peroxide decomposition [9,10].…”