ChemInform Abstract: SYNTHESE, STRUKTUR UND BIOLOGISCHE AKTIVITAET EINIGER INDOLO(2,3‐J)BENZACRIDINE UND EINIGER DIHYDROINDOLOBENZOPHENARSAZINE

Abstract

Im Zusammenhang mit pharmakologischen Untersuchungen werden einige der Titelheterocyclen synthetisiert.

Isolation and Synthesis of Biologically Active Carbazole Alkaloids

“…Examples of potential annulation modes are the pyrido- dimeric pyrido[4,3-c]carbazole, is under clinical trial for the treatment of cancer (Scheme 221). 492,493 The methods that were used for the synthesis of various isomeric pyrido[a]carbazoles and pyrido[c]carbazoles involve the photocyclization of indole derivatives, 320,321,334,479,[494][495][496][497][498] the functionalization of carbazole derivatives, [499][500][501][502][503] the Fischer indolization of hydrazone derivatives, [504][505][506] the base-induced cyclization of indole derivatives, 507 the Diels-Alder cycloaddition of indole-2,3-quinodimethane equivalents, 318,360,508 the intramolecular Diels-Alder reaction of substituted indoles, 473 the tandem reaction of 2-cyano-∆ 3 -piperidines, 509 the cyclization of aminoquinolines and azidoquinolines, 510 and the thermal cyclization of azidocarbazole derivatives. 451…”