ChemInform Abstract: Syntheses and Gastric Acid Antisecretory Properties of the H2‐Receptor Antagonist. N‐(3‐(3‐(1‐Piperidinylmethyl)phenoxy)propyl)thieno(3,4‐d)isothiazol‐3‐amine 1,1‐Dioxide and Related Derivatives.
Abstract:Sulfuration of the thienoisothiazolone (I) with phosphorus pentasulfide forms the corresponding thione (II) which is then methylated to give the methyl sulfide (IV).
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