ChemInform Abstract: Synthesis and Adrenergic Activity of a New Series of N‐Aryl Dicyclopropyl Ketone Oxime Ethers: SAR and Stereochemical Aspects.

Abstract

Synthesis and Adrenergic Activity of a New Series of N-Aryl Dicyclopropyl Ketone Oxime Ethers: SAR and Stereochemical Aspects. -The title compounds (31 examples) are evaluated for their in vitro and in vivo β-adrenergic receptor activity. Some of the most active compounds are (V). -(BLANC, M.; TAMIR, A.; AUBRIOT, S.; MICHEL, M. C.; BOUZOUBAA, M.; LECLERC, G.; DEMENGE, P.; J. Med. Chem. 41 (1998) 10,