ChemInform Abstract: Synthesis and Antibacterial Activities of Pleuromutilin Derivatives with Quinazolinone and Thioether Groups.

Abstract

Synthesis and Antibacterial Activities of Pleuromutilin Derivatives with Quinazolinone and Thioether Groups. -Ten novel pleuromutilin derivatives (V) are synthesized, which all exhibit higher antibacterial activity against S. aureus strains than pleuromutilin. -(YAO, Y.-P.; DAI, F.-Y.; DONG, K.-K.; MAO, Q.; WANG*, Y.-L.; CHEN, T.; J. Chem. Res. 35 (2011) 1, 4-7, http://dx.doi.org/10.3184/174751911x556675 ; Dep. Chem., Sichuan Univ., Chengdu 610064, Sichuan, Peop. Rep. China; Eng.) -K. Wilckens 23-197