ChemInform Abstract: Synthesis and Antimicrobial Activity of New Substituted 5‐(Pyridine‐3‐yl)‐1,3,4‐thiadiazoles and Their Sugar Derivatives.

Abstract

Synthesis and Antimicrobial Activity of New Substituted 5-(Pyridine-3-yl)--1,3,4-thiadiazoles and Their Sugar Derivatives. -New substituted pyridinylthiadiazoles, their sugar hydrazones [cf. (VIII)], acyclic C-nucleoside [cf. (X)] as well as corresponding thioglycoside derivatives [cf. (XX), (XXI)] are synthesized and evaluated for their antimicrobial activity. Most of the tested compounds exhibit moderate to high antimicrobial activity. -(EL-SAYED*, W. A.; METWALLY, M. A.; NADA, D. S.; MOHAMED, A. A.; ABDEL-RAHMAN, A. A.-H.; J. Heterocycl. Chem. 50 (2013) 2, 194-201, http://dx.