ChemInform Abstract: Synthesis and Antimicrobial Activity of Pyridopyrazole (V) and Pyrazolo[3,4‐d]dihydrothiazole (XI).

Deshmukh, M. B.; Deshmukh, S. A.; Jagtap, S. S.; Suryavanshi, A. W.; Jadhav, S. D.; Anbhule, Prashant V.

doi:10.1002/chin.201019145

Cited by 2 publications

(2 citation statements)

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“…Agglomerates were filtered and the obtained product was dried at room temperature overnight. [49] Characterization [50] • • Stability: Stability of drug substances changes due to polymorphism taking place.…”

Section: Sonocrystallizationmentioning

confidence: 99%

A Review: Meltsonocrystallization Technique Used for Improvement of Solubility

Sardar¹

2017

WJPPS

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Melt sonocrystallization method have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. It is a novel particle engineering technique to enhance dissolution of hydrophobic drugs that is having less water solubility and to study its effect on crystal properties of drug. It forms agglomerates with number of shallow circular pits on the surface leads to increase solubility by improving its shape from crystalline to amorphous that is obtain circular shape. Melt sonocrystallization process was developed for poorly soluble drugs in which these poorly soluble drugs melt was poured in deionized water maintained at 60 0 C and simultaneously subjected to ultrasonic energy.The agglomerates obtained after solidification of dispersed droplets were separated by filtration and dried at room temperature. Hence this review gives valuable information about on melt-sonocrystallization shows that there is increase in solubility of poorly water soluble drugs.

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Section: Sonocrystallizationmentioning

confidence: 99%

A Review: Meltsonocrystallization Technique Used for Improvement of Solubility

Sardar¹

2017

WJPPS

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“…These derivatives are used as anti-oxidant 5 for rubber , linseed oil and as disperse dyes 6 . They possess wide range of pharmacological activities as hypoglycemic 7 , antimicrobial 8,9 , anticonvulsive 10 , antiinflammatory 11 , antihistaminic 12 , anti coagulant 13 , and anti-rheumatic 14 agents etc. Some thiazinopyrazole derivatives have been synthesized and screened their antimicrobial activity [15][16][17] .…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Some Thiazino-pyrazoles as Potential Fungicides

Kedia¹,

Singh²,

Singh³

2012

Orientjchem.

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ABSTRACT4-Arylmethylene-2,4-dihydro-2-arylthioanilido-5-methyl-3H-pyrazol-3-ones(2) were prepared by the condensation of 2,4-dihydro-2-arylthioanilido-5-methyl-3H-pyrazol -3-ones (1) with aromatic aldehydes in the presence of glacial acetic acid. The synthesized compounds (2) reacted with phenyl thiourea in presence of alcoholic KOH at reflux temperature to give 1-arylthioanilido-3-methyl-4-aryl-6-phenylimino -4,7-dihydro-1, 3-thiazino [5,4-d] pyrazoles (3). The synthesised compounds (3) have been screened for their fungicidal activities against fungi A. fumigatus and C. albicans at different concentrations.

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ChemInform Abstract: Synthesis and Antimicrobial Activity of Pyridopyrazole (V) and Pyrazolo[3,4‐d]dihydrothiazole (XI).

Cited by 2 publications

References 1 publication

A Review: Meltsonocrystallization Technique Used for Improvement of Solubility

A Review: Meltsonocrystallization Technique Used for Improvement of Solubility

Synthesis of Some Thiazino-pyrazoles as Potential Fungicides

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