“…Benzothiazole derivatives present a wide range of biological activities such as, antitumor, antimicrobial, antitubercular, antimalaria, anticonvulsant, anthelmintic, antiinflammatory and analgesic among others, for which, they are of great pharmacological and medicinal interest [1][2][3][4][5][6][7][8]. The incorporation of different groups in the thiazol ring or in both rings improves their pharmacological properties, as reported for the 2-amino-5-(trifluoromethoxy)benzothiazole derivative, named riluzol, which has a NH 2 group in the thiazole ring and a O-CF 3 group in the benzene ring.…”