Chemischer Informationsdienst
 1982
DOI: 10.1002/chin.198215329
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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL PROPERTIES OF P‐AZIDOPHENYLALANINE13‐α‐MELANOTROPIN, A POTENT PHOTOAFFINITY LABEL FOR MSH RECEPTORS

Alex N. Eberlé1,
P.N.E. de Graan2,
W. Huebscher3

Abstract: Die Titelverbindung ([Pap′3 1a‐ MSH) ‐ in der acetylierten Form (IIIc) ‐ wird in homogener Lösung nach klassischer r Fragmentkondensationsmethode synthetisiert [(1) + (II) ‐+ (IIIa)‐(IIIb)‐(IIIc)] und hinsichtlich ihrer biologischen Eigenschaften (Pigmentverteilungs‐Aktivität, Tyrosinase‐stimulierende Aktivität) vergleichend mit α‐Melanotropin detailliert untersucht.

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