ChemInform Abstract: Synthesis and Characterization of New Phthalhydrazothiazole Derivatives: A Preliminary Investigation on Their Activity Against Hepatocellular Carcinoma.

Abstract

A straightforward and efficient synthesis of compounds containing both a thiazole and phthalazine moiety is described. Some of these compounds, especially derivative (VIId), show encouraging activity towards liver tumor cells. -(CARDIA*, M. C.; DISTINTO, S.; MACCIONI, E.; PLUMITALLO, A.; SANNA, L.; SANNA, M. L.; VIGO, S.; J. Heterocycl. Chem. 46 (2009) 4, 674-679; Dip. Farm. Chim. Tecnol., Univ. Cagliari, I-09124 Cagliari, Italy; Eng.) -R. Staver 49-163