ChemInform Abstract: Synthesis and Evaluation of Mono‐, Di‐, and Trifluoroethenyl‐GABA Derivatives as GABA‐T Inhibitors.

Abstract

The fluorinated analogues (VII), (VIII), and (XIV) of vinyl‐GABA (I) are prepared from the vinyl lactam (II) or 4‐bromobutene (IX) as shown in the reaction scheme.