ChemInform Abstract: Synthesis and Pharmacological Profile of FCE 28654: A Water‐Soluble and Injectable ACAT Inhibitor.

Abstract

Synthesis and Pharmacological Profile of FCE 28654: A Water-Soluble and Injectable ACAT Inhibitor. -The title compound (V) positively modifies blood and hepatic cholesterol levels in animals. -(CHIARI, A.; FANCELLI, D.; LOVISOLO, P. P.; RADICE, A.; SAVOIA, L.; SEVERINO, D.; GHISELLI, G.; Bioorg. Med. Chem. Lett. 5 (1995) 15, 1581-1586 Pharm. Pharm. Res. Inst., I-20014 Nerviano, Milan, Italy; EN)