ChemInform Abstract: Synthesis of Marine Natural Product (‐)‐Pericosine E.

Abstract

Synthesis of Marine Natural Product (-)-Pericosine E. -The first synthesis of (-)-pericosine E is described. -(MIZUKI, K.; IWAHASHI, K.; MURATA, N.; IKEDA, M.; NAKAI, Y.; YONEYAMA, H.; HARUSAWA, S.; USAMI*, Y.; Org. Lett. 16 (2014) 14, 3760-3763, http://dx.

Total Synthesis of (−)-Sigillin A: A Polychlorinated and Polyoxygenated Natural Product

“…12b Then, enone 22 was employed in the installation of a hydroxy group at the C-9 position. In situ Rubottom oxidation 13 of triethylsiloxy diene using DMDO led to successful installation of a hydroxy group with the desired configuration to afford diol 23 as a single diastereomer. 14 The unpredicted diol 23 was obtained as a result of the loss of TMS protecting group of the tertiary hydroxy group.…”