Abstract:Tetrasubstituted Pyrazinones Derived from the Reaction of Praziquantel with N-Bromosuccinimide. -The cytotoxicity of the synthesized pyrazones are tested against several protozoan parasites. Compound (VIId) possesses the highest activity against L. donovani parasite. -(ZHAO, Q.; WANG, C.; EZELL, E. L.; DONG, Y.; VENNERSTROM*, J. L.; Tetrahedron Lett. 55 (2014) 32, 4463-4465, http://dx.
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