ChemInform Abstract: Two‐Step Allylic Carbon Insertion Between Ketone Carbonyl and α Carbons Giving α‐Quaternary α‐Vinyl Ketones.

Abstract

Insertion reactions O 0288Two-Step Allylic Carbon Insertion Between Ketone Carbonyl and α Carbons Giving α-Quaternary α-Vinyl Ketones. -A two-step sequence involves a highly regioselective allenylation of ketones followed by rearrangement of the resulting α-allenyl alcohols with NBS. It allows the synthesis of α-quarternary α-vinyl ketones. -(HE, J.-Q.; SHIBATA, D.; OHNO, C.; OKAMOTO*, S.; Tetrahedron Lett. 49 (2008) 47, 6724-6727; Dep. Mater. Life Chem., Kanagawa Univ., Kanagawa, Yokohama 221, Japan; Eng.) -Mais 10-041