Chemistry and Biological Activity of Mustard Oil: Therapeutic Benefits and Risk to Healthcare

Akhtar, Md Jawaid; Khan, Shah Alam

doi:10.1007/s43450-023-00450-2

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2024

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Cited by 4 publications

References 79 publications

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Estimating the changes in mechanically expressible oil in terms of content and quality from ohmic heat treated mustard (Brassica juncea) seeds by Vis–NIR–SWIR hyperspectral imaging

Hamad,

Chakraborty,

Kumar

2024

Food Measure

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Estimating the changes in mechanically expressible oil in terms of content and quality from ohmic heat treated mustard (Brassica juncea) seeds by Vis–NIR–SWIR hyperspectral imaging

Hamad,

Chakraborty,

Kumar

2024

Food Measure

View full text Add to dashboard Cite

Leveraging Nano Silica and plant growth promoting rhizobacteria (PGPR) isolated from Gangetic riparian zone to Combat Pendimethalin Toxicity in Brassica juncea

Sharma,

Tripathi,

Tiwari

et al. 2024

Plant Nano Biology

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Osteogenic Protection against Fine Dust with Erucic Acid-Induced Exosomes

Kim,

Kim

2024

JFB

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Fine dust causes various disorders, including cardiovascular, neurological, renal, reproductive, motor, systemic, respiratory, and cancerous diseases. Therefore, it is essential to study functional materials to prevent these issues. This study investigated the beneficial effects of erucic acid against fine dust using methods such as miRNA profiling, quantitative PCR, flow cytometry, ELISA, and Alizarin O staining. Erucic acid effectively suppresses inflammation and upregulates osteogenic activators in fibroblasts exposed to fine dust. Additionally, erucic acid-induced exosomes (EIEs) strongly counteract the negative effects of fine dust on osteocytic differentiation and inflammation. Despite fine dust exposure, EIEs promoted osteocytic differentiation in adipose-derived stem cells (ASCs) and enhanced osteogenesis and phagocytosis in macrophages. The significant upregulation of RunX2 and BMP7 by EIEs indicates its strong role in osteocytic differentiation and protection against the effects of fine dust. EIEs also boosts immune activity and acts as an osteogenic trigger for macrophages. MicroRNA profiling revealed that EIEs dramatically upregulated miRNAs, including hsa-miRNA-1301-3p, hsa-miRNA-1908-5p, hsa-miRNA-423-5p, and hsa-miRNA-122-5p, which are associated with osteogenic differentiation and immunity. Therefore, EIEs show potential as biomaterials to prevent environment-borne diseases.

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Chemistry and Biological Activity of Mustard Oil: Therapeutic Benefits and Risk to Healthcare

Cited by 4 publications

References 79 publications

Estimating the changes in mechanically expressible oil in terms of content and quality from ohmic heat treated mustard (Brassica juncea) seeds by Vis–NIR–SWIR hyperspectral imaging

Estimating the changes in mechanically expressible oil in terms of content and quality from ohmic heat treated mustard (Brassica juncea) seeds by Vis–NIR–SWIR hyperspectral imaging

Leveraging Nano Silica and plant growth promoting rhizobacteria (PGPR) isolated from Gangetic riparian zone to Combat Pendimethalin Toxicity in Brassica juncea

Osteogenic Protection against Fine Dust with Erucic Acid-Induced Exosomes

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