Chikungunya Virus, Cameroon, 2006

Peyrefitte, Christophe N.; Rousset, Dominique; Pastorino, Boris; Pouillot, Régis; Bessaud, Maël; Tock, Fabienne; Mansaray, Helene; Merle, Olivier L.; Pascual, Aurélie; Paupy, Christophe; Vessière, Aurélia; Imbert, Patrice; Tchendjou, Patrice; Durand, Jean Paul; Tolou, Hugues; Grandadam, Marc

doi:10.3201/eid1305.061500

Cited by 130 publications

(122 citation statements)

References 13 publications

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“…Cette épidémie s'est par la suite étendue à l'île Maurice (Julvez et al, 1998 (Robinson, 1955 ;Moore et al, 1974 ;Kalunda et al, 1985 ;. Plus récemment, une épidémie touchant près de 50 000 personnes est survenue en République Démocratique du Congo, à Kinshasa, en 1999-2000(Pastorino et al, 2004, au Cameroun (Peyrefitte et al, 2006) et au Gabon (Leroy, 2007 en 2007. En dehors de la zone afro-tropicale, le CHIKV sévit également en Asie où il a été signalé pour la première fois en 1958 en Thaïlande (Rao, 1966 ;Halstead et al, 1969).…”

Section: Mise Au Pointunclassified

Aedes albopictus, vecteur des virus du chikungunya et de la dengue à la Réunion : biologie et contrôle

Delatte

Paupy

Dehecq³

et al. 2008

Parasite

193

124

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Summary : AEDES ALBOPICTUS, VECTOR OF CHIKUNGUNYA AND DENGUE VIRUSES IN REUNION ISLAND: BIOLOGY AND CONTROLChikungunya virus (CHIKV) and dengue virus (DENV) are mosquitoborne viruses transmitted by the Aedes genus. Dengue is considered as the most important arbovirus disease throughout the World. Chikungunya, known from epidemics in continental Africa and Asia, has up to now been poorly studied. It has been recently responsible for the severe 2004-2007 epidemic reported in the Indian Ocean (IO), which has caused several serious health and economic problems. This unprecedented epidemic of the IO has shown severe health troubles with morbidity and death associated, which had never been observed before. The two major vectors of those arboviruses in the IO area are Aedes aegypti and Aedes albopictus. The latest is considered as the main vector in most of the islands of the area, especially in Reunion Island. Ae. albopictus showed strong ecological plasticity. Small disposable containers were the principal urban breeding sites, and preferred natural developmental sites were bamboo stumps and rock holes in periurban and gully areas. The virus has been isolated from field collected Ae. albopictus females, and in two out of 500 pools of larvae, demonstrating vertical transmission. Experimental works showed that both Ae. albopictus and Ae. aegypti from west IO islands are efficient vectors of dengue and chikungunya viruses. Since 2006 and all along the epidemic of CHIKV, measures for the control of larvae (temephos then Bacillus thuringiensis) and adults (fenitrothion, then deltamethrine) of Ae. albopictus where applied along with individual and collective actions (by the use of repellents, and removal of breeding sites around houses) in Reunion Island. In order to prevent such epidemics, a preventive plan for arboviruses upsurge is ongoing processed. This plan would allow a quicker response to the threat and adapt it according to the virus and its specific vector. Résumé : Les virus du chikungunya (CHIKV) et de la dengue (DENV) sont transmis par des moustiques du genre

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Section: Mise Au Pointunclassified

Aedes albopictus, vecteur des virus du chikungunya et de la dengue à la Réunion : biologie et contrôle

Delatte

Paupy

Dehecq³

et al. 2008

Parasite

193

124

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“…In the Maldives, approximately 12 000 suspected chikungunya fever cases were reported during the 2006-2007 outbreak (Yoosuf et al, 2009). Similarly, CHIKV outbreaks were also reported from Gabon (Peyrefitte et al, 2008), Cameroon (Peyrefitte et al, 2007) and Thailand (Theamboonlers et al, 2009). Moreover, the first indigenous CHIKV outbreak in Europe was reported from Italy in 2007 (Rezza et al, 2007).…”

Section: Introductionmentioning

confidence: 98%

Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore

Hapuarachchi

Bandara

Sumanadasa

et al. 2009

Journal of General Virology

129

135

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Chikungunya fever swept across many South and South-east Asian countries, following extensive outbreaks in the Indian Ocean Islands in 2005. However, molecular epidemiological data to explain the recent spread and evolution of Chikungunya virus (CHIKV) in the Asian region are still limited. This study describes the genetic Characteristics and evolutionary relationships of CHIKV strains that emerged in Sri Lanka and Singapore during 2006-2008. The viruses isolated in Singapore also included those imported from the Maldives (n51), India (n52) and Malaysia (n531). All analysed strains belonged to the East, Central and South African (ECSA) lineage and were evolutionarily more related to Indian than to Indian Ocean Islands strains. Unique genetic characteristics revealed five genetically distinct subpopulations of CHIKV in Sri Lanka and Singapore, which were likely to have emerged through multiple, independent introductions. The evolutionary network based on E1 gene sequences indicated the acquisition of an alanine to valine 226 substitution (E1-A226V) by virus strains of the Indian sublineage as a key evolutionary event that contributed to the transmission and spatial distribution of CHIKV in the region. The E1-A226V substitution was found in 95.7 % (133/139) of analysed isolates in 2008, highlighting the widespread establishment of mutated CHIKV strains in Sri Lanka, Singapore and Malaysia. As the E1-A226V substitution is known to enhance the transmissibility of CHIKV by Aedes albopictus mosquitoes, this observation has important implications for the design of vector control strategies to fight the virus in regions at risk of chikungunya fever.

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“…The disease is called ''buka-buka" in Congo, meaning ''broken-broken'' reflecting the incapacitating arthralgias or to become contorted (Mohan et al, 2010). Chikungunya (CHIK) is caused by chikungunya virus (CHIKV), formerly occurs only as an episodic arbovirus, is now a worldwide public health problem (Peyrefitte et al, 2007). This disease is gradually assuming a major health problem with potentially life-threatening and debilitating arthritis (Rashad et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of IgG and IgM antibodies to Chikungunya virus among outpatients with febrile illness attending University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria

Akinola¹,

El-Yuguda²,

Bukbuk³

et al. 2017

Afr. J. Microbiol. Res.

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In Nigeria, there is paucity of information on the epidemiology of infections due to Chikungunya virus (CHIKV) especially among patients with febrile illness. Cases of febrile illness are usually associated with malaria and typhoid fever without considering the possibility of viral aetiology. This study was designed to determine the prevalence and identify other epidemiological parameters of CHIKV infections among outpatients with febrile illness attending University of Maiduguri Teaching Hospital, Nigeria. Sera from 370 patients were tested for presence of CHIKV immunoglobin (Ig) IgM and IgG antibodies using the enzyme-linked immunosorbent assay (ELISA). Of the 370 sera tested, 39 (10.5%) were positive for presence of CHIKV antibodies. A total of 24 (6.5%) tested positive for CHIKV IgM only, while none (0.0%) was positive for the presence of CHIKV IgG only. Fifteen (4.1%) of the serum samples simultaneously reacted to both IgG and IgM antibodies. A significant difference (p<0.0001) was observed in the distribution of CHIKV antibodies in relation to gender. The males had prevalence of 8.5% IgM antibodies as against 4.6% in females, 4.6% of females were positive for both CHIKV IgG and IgM antibodies, compared to 3.4% in males. The age group ≤60 years and the undisclosed age group were positive for the presence of CHIKV IgG and/or IgM antibodies. No significant difference was observed in the seasonal prevalence of CHIKV antibodies among the study subjects. Analysis of the prevalence of CHIKV antibodies in relation to clinical presentation in the patients revealed that headache and fever were the most frequently encountered ailments.

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Chikungunya Virus, Cameroon, 2006

Cited by 130 publications

References 13 publications

Aedes albopictus, vecteur des virus du chikungunya et de la dengue à la Réunion : biologie et contrôle

Aedes albopictus, vecteur des virus du chikungunya et de la dengue à la Réunion : biologie et contrôle

Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore

Prevalence of IgG and IgM antibodies to Chikungunya virus among outpatients with febrile illness attending University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria

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