In recent years, due to the shortage of water resources and the fragile ecological environment in arid areas, the relationship between vegetation and water resources has been relatively close. The unreasonable allocation of water resources and the excessive demand for ecological water use have led to ecological and environmental problems such as river interruption, land desertification, and the extensive withering of vegetation in arid areas; therefore, rapid, accurate estimation of the vegetation ecological water demand has become a hot research topic in related fields. In this study, we classified the land use types in the lower reaches of the Kokyar River Basin based on Sentinel-2A data and calculated the water requirements of each type of vegetation using a combination of the area quota method and improved Penman–Monteith (PM) based on different vegetation coverage levels. The results revealed that in 2020, the water demand of planted woodlands within 0–2 km of the watershed will be the highest, and the water demand of naturally growing arboreal woodlands will be the lowest, and the water demand of the surrounding desert riparian vegetation forests will be very small in relation to the ecological base flow and will not affect the downstream water use for agriculture, industry, and domestic use for the time being. The ecological water demand of the vegetation in the study area can be accurately estimated using Sentinel-2A data, and the research results provide technical support and a theoretical basis for rapid estimation of the ecological water demand of vegetation in typical riparian forests in arid areas and for the allocation of water resources.