Chinchilla laniger can be used as an experimental model for Taenia solium taeniasis

Maravilla, Pablo; Garza-Rodriguez, Adriana; Gómez-D́iaz, Benjamín; Jiménez-González, Diego Emiliano; Toral-Bastida, Elizabeth; Martinez-Ocaña, Joel; West, Brett J.; Molina, Nadia Alvarado; Garcia-Cortes, Ramon; Kawa-Karasik, Simón; Romero‐Valdovinos, Mirza; Ávila, Guillermina; Flisser, Ana

doi:10.1016/j.parint.2011.06.002

Cited by 14 publications

(15 citation statements)

References 20 publications

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“…Several animal models such as rhesus monkey, white rat, white mouse, cat, gerbil, guinea pig, gibbon for taeniasis have been evaluated . In the young dog, cysticerci survived only for 8 days after infection, whereas in macaques, cats and rabbits, in spite of being made immunodepressed, they did not develop adult T. solium tapeworms .…”

Section: Animal Models For Taeniasismentioning

confidence: 99%

“…In the young dog, cysticerci survived only for 8 days after infection, whereas in macaques, cats and rabbits, in spite of being made immunodepressed, they did not develop adult T. solium tapeworms . However, in chinchilla and hamster, researchers could get viable eggs after proglottid infection and these eggs were capable of developing to cysticerci in another host . Hence, only these two animal models are considered for further discussion here.…”

Section: Animal Models For Taeniasismentioning

confidence: 99%

“…Several animal models such as rhesus monkey, white rat, white mouse, cat, gerbil, guinea pig, gibbon for taeniasis have been evaluated. 10,11,29,47 In the young dog, cysticerci survived only for 8 days after infection, whereas in macaques, cats and rabbits, in spite of being made immunodepressed, they did not develop adult T. solium tapeworms. 10 However, in chinchilla and hamster, researchers could get viable eggs after proglottid infection and these eggs were capable of developing to cysticerci in another host.…”

Section: Animal Models For Taeniasismentioning

confidence: 99%

“…10 However, in chinchilla and hamster, researchers could get viable eggs after proglottid infection and these eggs were capable of developing to cysticerci in another host. 29 Hence, only these two animal models are considered for further discussion here.…”

Section: Animal Models For Taeniasismentioning

confidence: 99%

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Recent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis

Arora

Tripathi

Kumar

et al. 2017

Parasite Immunology

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Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tapeworm). Hence, developing an animal model for T. solium that mimics its natural course of infection is quite challenging. We have reviewed here the animal models frequently used to study immunopathogenesis of cysticercosis and also discussed their usefulness for NCC studies. We found that researchers have used mice, rats, guinea pigs, dogs, cats and pigs as models for this disease with varying degrees of success. Mice and rats models have been utilized extensively for immunopathogenesis studies due to their relative ease of handling and abundance of commercially available reagents to study these small animal models. These models have provided some very exciting results for in-depth understanding of the disease. Of late, the experimentally/naturally infected swine model is turning out to be the best animal model as the disease progression closely resembles human infection in pigs. However, handling large experimental animals has its own challenges and limitations.

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Section: Animal Models For Taeniasismentioning

confidence: 99%

Section: Animal Models For Taeniasismentioning

confidence: 99%

Section: Animal Models For Taeniasismentioning

confidence: 99%

Section: Animal Models For Taeniasismentioning

confidence: 99%

See 2 more Smart Citations

Recent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis

Arora

Tripathi

Kumar

et al. 2017

Parasite Immunology

View full text Add to dashboard Cite

show abstract

“…Areas of study include otitis media, cholesteatoma, therapeutic treatment of aural disease, noise and chemical-induced hearing loss, Ménière's disease, tinnitus, perilymphatic fistulas, cochlear implants, superior canal dehiscence, tympanic membrane perforation repair, stem cell transplants, and otic drug safety testing (Martin, 2012b). Other areas of research utilizing chinchillas include hypothyroidism model development (Martin et al, 2005), repair of dural tears (Shah et al, 2007), evaluation of pathogenic biofilm mediators of Pseudomonas aeruginosa (Byrd et al, 2011), and propagation of Taenia solium taeniasis eggs and adults for further study (Maravilla et al, 2011). Other areas of research utilizing chinchillas include hypothyroidism model development (Martin et al, 2005), repair of dural tears (Shah et al, 2007), evaluation of pathogenic biofilm mediators of Pseudomonas aeruginosa (Byrd et al, 2011), and propagation of Taenia solium taeniasis eggs and adults for further study (Maravilla et al, 2011).…”

Section: B Uses In Researchmentioning

confidence: 99%

Biology and Diseases of Chinchillas

Hsu

Chan²,

Wheler

2015

Laboratory Animal Medicine

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Inactivation of exogenous endoparasite stages by chemical disinfectants: current state and perspectives

Daugschies¹,

Bangoura²,

Lendner³

2013

Parasitol Res

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Chemical disinfection is common practice and inevitable to achieve sufficient control over parasites particularly in intensive animal housing systems. To identify suitable chemicals, reliable data on antiparasitic efficacy of disinfectants are required. This review summarizes recently published experience with procedures applied to evaluate the viability of a variety of endoparasites following physical or chemical stress. It is concluded that laboratory models used to assess antiparasitic efficacy of e.g. commercial disinfectants should consider the most resistant stages of both helminths and protozoa, i.e. ascarid eggs and coccidia oocysts. To ensure reproducibility and transparency, standardized protocols are pivotal. Such protocols are established on a national level (e.g. DVG guidelines in Germany); however, internationally accepted certification procedures are currently lacking.

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Chinchilla laniger can be used as an experimental model for Taenia solium taeniasis

Cited by 14 publications

References 20 publications

Recent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis

Recent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis

Biology and Diseases of Chinchillas

Inactivation of exogenous endoparasite stages by chemical disinfectants: current state and perspectives

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