Chios mastic gum: A validated method towards authentication

Svingou, Despoina; Mikropoulou, Eleni V.; Pachi, Vasiliki K.; Smyrnioudis, Ilias; Halabalaki, Maria

doi:10.1016/j.jfca.2022.104997

Cited by 6 publications

(1 citation statement)

References 20 publications

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“…3 Mastic is rich in terpenes, comprising 65%-70%, of which about 38% and 27% represent the acidic and neutral fractions of triterpenes, respectively. 1 Numerous chromatographic methods for the analysis of terpene compounds in mastic have been explored, including GC-MS, 4,5 , liquid chromatography high-resolution tandem mass spectrometry (LC-HRMS/MS), 6 supercritical fluid chromatography (SFC)-UV/MS, 7 HPLC-evaporative light scattering detection (ELSD), 8 and HPLC-atmospheric pressure chemical ionization (APCI)-MS. 9 These methods have mainly focused on studying triterpenes such as isomasticadienonic, masticadienonic, oleanonic, and moronic acids.…”

Section: Introductionmentioning

confidence: 99%

Systematic qualitative analysis of terpenes in mastic (Pistacia lentiscus L.) extract and their fragmentations by UHPLC‐Q‐Orbitrap‐HRMS

Kahaer,

Abdulla,

et al. 2024

Phytochemical Analysis

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IntroductionMastic is a natural resin produced by Pistacia lentiscus L. (Anacardiaceae). The beneficial properties of this resin are attributed to its triterpenes and volatile compounds.ObjectiveThis study was conducted to screen and characterize the terpenes in mastic ethyl acetate extract (M‐Ex).MethodsAn ultrahigh‐performance liquid chromatography coupled to quadrupole Orbitrap high‐resolution mass spectrometry (UHPLC‐Q‐Orbitrap‐HRMS) method was developed for the qualitative analysis of terpenes in M‐Ex. We utilized in‐house‐isolated compounds as reference substance (Rs), including monoterpenes (A) with α‐pinane structures, tetracyclic triterpene (B) containing tirucallane skeletons, and pentacyclic triterpene (C) belonging to olean, moronic, amyrone, and lupane types. Based on the mass spectrometric characteristics of the above compounds, and the difference in characteristic diagnostic fragment ions (DFIs) in isomeric compounds, the terpene compounds were further identified in M‐Ex.ResultsOut of a total of 70 compounds, including monoterpenes and tetra‐, and pentacyclic triterpenes, 20 were accurately determined by Rs, retention time (RT), and DFIs.Based on the cleavage patterns summarized from the above 20 compounds and with reference to the reported literature, another 50 compounds were putatively identified. Based on our discovery, six terpenic acids with A‐seco‐tirucallane types and one monoterpene dimer were identified for the first time in mastic.ConclusionOur research serves not only as a foundation for the rapid identification and screening of terpene compounds in mastic but also as a supplementary basis for the identification of such compounds in other types of resins.

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Section: Introductionmentioning

confidence: 99%

Systematic qualitative analysis of terpenes in mastic (Pistacia lentiscus L.) extract and their fragmentations by UHPLC‐Q‐Orbitrap‐HRMS

Kahaer,

Abdulla,

et al. 2024

Phytochemical Analysis

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Non‐Conductive and Conductive Washable Amylopectin‐Mastic Gum Adhesives for On‐Skin Applications

Al Boustani,

Xu,

Teshima

et al. 2024

Adv Materials Technologies

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The investigation of a skin adhesive based on amylopectin and mastic gum for attaching skin sensors are reported. The material provides reliable adhesion and is, at the same time, readily washable from the skin due to the hydrophilic character of the amylopectin compound. The effect of water and glycerol content on the adhesion properties in combination with polyimide‐based substrates is assessed and optimize the material for homogeneous and washable on‐skin applications. This results show that the adhesive material can withstand a shear stress of 88.7 ± 5.30 kPa in a lap shear test. The adhesive material can also be easily rendered conductive by adding sodium chloride. Impedance spectroscopy is performed on the conductive adhesive material to assess the impedance behavior during drying conditions over 24 h in comparison to commercial electrolyte gel. While the conductive adhesion material's initial impedance is slightly higher than the commercial gel, the long‐term assessment demonstrates a significantly improved stability over time. In conclusion, this study develops a skin adhesive combining amylopectin and mastic gum, demonstrating promising adhesion strength and conductivity properties, thus potentially addressing current stability challenges in skin‐sensor applications.

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Seven New Noroleanane Triterpenoids from Mastic and Their NO Inhibitory and Cytotoxic Activities

An,

Wang,

Sun

et al. 2024

Chemistry & Biodiversity

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Mastic is a natural resin produced by Pistacia lentiscus L. (Anacardiaceae) with high medicinal value and have been traditionally used as Uighur imported medicine for centuries. In this study, 16 triterpenoids including seven new norleanane triterpenoids (1‐7), along with nine known oleanane triterpenoids (8‐16), were isolated from the mastic. Their chemical structures were determined on the basis of extensive spectroscopic analyses (including IR, UV, ESI‐HR‐MS and NMR spectroscopy) and single‐crystal X‐ray diffraction. Compounds 4‐7, 11, 14 and 16 showed strong inhibitory NO production in LPS‐induced RAW264.7 cells with IC50 values 7.44‐9.76 μM, respectively (positive control dexamethasone, 9.93 ± 1.17 μM). Furthermore, compounds 3 and 12 significantly inhibited the growth of SW480 cells, compound 3 showed the most pronounced inhibitory effect with an IC50 of 2.30 ± 0.38 μM.

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Chios mastic gum: A validated method towards authentication

Cited by 6 publications

References 20 publications

Systematic qualitative analysis of terpenes in mastic (Pistacia lentiscus L.) extract and their fragmentations by UHPLC‐Q‐Orbitrap‐HRMS

Systematic qualitative analysis of terpenes in mastic (Pistacia lentiscus L.) extract and their fragmentations by UHPLC‐Q‐Orbitrap‐HRMS

Non‐Conductive and Conductive Washable Amylopectin‐Mastic Gum Adhesives for On‐Skin Applications

Seven New Noroleanane Triterpenoids from Mastic and Their NO Inhibitory and Cytotoxic Activities

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