Chiral Diselenide Ligands for the Asymmetric Copper‐Catalyzed Conjugate Addition of Grignard Reagents to Enones.

Abstract

reactions of organo-metal compounds reactions of organo-metal compounds O 0350 52 -066 Chiral Diselenide Ligands for the Asymmetric Copper-Catalyzed Conjugate Addition of Grignard Reagents to Enones. -Cyclic enones (I) undergo Cu-catalyzed addition of Grignard reagents (II) in the presence of chiral diselenide oxazoline ligand with moderate levels of asymmetric induction. -(BRAGA, ANTONIO L.; SILVA, SANDRA J. N.; LUEDTKE, DIOGO S.; DREKENER, ROBERTA L.; SILVEIRA, CLAUDIO C.; ROCHA, JOAO B. T.; WESSJOHANN, LUDGER A.; Tetrahedron Lett. 43 (2002) 41, 7329-7331; Dep. Quim., Univ. Fed.