Chirality at nanoscale for bioscience

Abstract

Chirality is a ubiquitous physical attribute in nature. Since the development of nanomaterials, the considerable interest in this research field has increased, extending the study of chirality to the nanoscale....

Customizable nano-sized colloidal tetrahedra by polymerization-induced particle self-assembly (PIPA)

“…The seeds were then used for aqueous seeded polymerization of HPMA, producing the PDMA-b-PBzMA-b-PHPMA triblock terpolymer. 1 H NMR shows an average composition of PDMA 70 -b-PBzMA 96 -b-PHPMA 258 (Fig. S3e †).…”

“…Colloidal molecules (CMs) are well-defined colloidal clusters with molecule-like geometry and symmetry, which have unique applications in bioscience, 1 catalysis, 2 plasmonics, 3 photonics, 4,5 and as subunits for hierarchical self-assembly into complex structures. [6][7][8][9] For example, colloidal tetrahedra (CTs) possess CH 4 -like architecture and the simplest isotropic dipolar symmetry, 10 and the self-assembly of CTs generates colloidal cubic diamond crystal structures that have potential applications in photonics.…”

Self-recovery of chiral microphase separation in an achiral diblock copolymer system

“…[16][17][18][19] These research studies are of great signicance in fundamental science and guide the design of novel chiral materials. [20][21][22][23] Self-assembly of block copolymers (BCPs), a typical bottom-up strategy for the facile fabrication of multi-morphological nanostructures, [24][25][26][27] has also been applied to design and construct advanced chiral materials with regular periodicity and controlled handedness. [28][29][30][31][32][33][34] By providing one or two BCP fragments containing chiral centers, transfer of chiral characteristics from the molecular level to the morphological level would occur during bulk microphase separation (MPS).…”

Understanding of chiral site-dependent enantioselective identification on a plasmon-free semiconductor based SERS substrate

“…[1][2][3][4] Although enantiomers have similar physicochemical properties, they exhibit completely different physiological effects in terms of biological activity, toxicity, and pharmacological actions. 5 A characteristic example of enantiomers is 3,4-dihydroxyphenylalanine (DOPA).…”