2019
DOI: 10.2174/2210303109666190404143906
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Chitosan Applications on Pharmaceutical Sciences: A Review

Abstract: Background: Chitosan (CS) is a biomaterial derived from chitin, known for its excellent biological properties. One of the most interesting features of CS is its potential for chemical derivatization, which makes it a versatile material and allows to expand its applications. In the last years, the interest on this polymer and its pharmaceutical applications has notably increased. This biopolymer is being widely studied for its interesting properties, such as bioadhesion, antimicrobial activity, biocompatibility… Show more

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Cited by 6 publications
(3 citation statements)
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“…1). [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] Industrial chitin processing 23 (Fig. 2) first requires the chemical treatment of gathered seafood waste.…”
Section: Introductionmentioning
confidence: 99%
“…1). [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] Industrial chitin processing 23 (Fig. 2) first requires the chemical treatment of gathered seafood waste.…”
Section: Introductionmentioning
confidence: 99%
“…El quitosano es un polímero natural formado por unidades de N-acetil D-glucosamina, derivado de la desacetilación alcalina de la quitina, el cual se encuentra disponible en el exoesqueleto de crustáceos, algas y hasta en un tercio del total de la pared celular en hongos (3) . Este polímero es soluble en agua, exhibe propiedades bioactivas como antimicrobiano, inmunomodulador y antioxidante, y además, es reconocido como un compuesto natural e inocuo (4,5) , por lo que es apropiado para su uso en la industria de alimentos (6) .…”
unclassified
“…Chitosan (CHT), a natural cationic glycosaminoglycan, is widely used for 3D scaffold preparation and ensuing tissue regeneration due to its unique properties including biocompatibility, biomimicking, biodegradability, bioactivity, and crosslinking ability as reviewed by several outstanding reports. In addition, this important biomaterial can be formulated into various platforms such as, but not limited to, sponges, cryogels, and dressings for drug delivery and tissue engineering applications [17][18][19][20] . Crosslinking agents for chitosan (glutaraldehyde, genipin, or tripolyphosphate) not only increase the mechanical properties of the scaffold but also prolong the retention time of the scaffold in vivo [21][22][23][24] .…”
mentioning
confidence: 99%