Chitosan conjugated with deoxycholic acid and gallic acid: A novel biopolymer‐based additive antioxidant for polyethylene

Abstract

Chitosan, as a novel bioadditive antioxidant for commodity polymer, is proposed. Chitosan is successfully conjugated with deoxycholic acid and gallic acid (chitosan-DC-GA) via a simple reaction using the 1-ethyl-3-(3 0 -dimethylaminopropyl) carbodiimide/Nhydroxysuccinimide conjugating agent at room temperature in a heterogeneous system. Chitosan-DC-GA shows a deoxycholic acid (DC) and gallic acid (GA) content of about 40% each. Chitosan-DC-GA exhibits DPPH radical scavenging ability with EC 50 1 mg mL 21 based on the EPR technique evaluation. A model case study of chitosan-DC-GA with low-density polyethylene (LDPE) confirms improvement in compatibility, as seen from the sheet clarity, as well as the good dispersion of chitosan-DC-GA in LDPE matrices, as observed by scanning electron microscope.

Immunomodulatory role of chitosan‐based nanoparticles and oligosaccharides in cyclophosphamide‐treated mice

“…The antioxidant activity of chitosan‐based conjugates chiefly depends on the amount of the grafted antioxidant molecules on the chitosan backbone . Based on the earlier study conducted (results not shown), we found that increasing the concentration of GA further did not result in an increased encapsulation, so the said parameters were followed throughout the experiment.…”

“…Therefore, the water solubility of cGANP saw a significant increase as compared to the native chitosan. Similar results were also reported in previous studies wherein conjugation of phenolic acids to chitosan induced an increase in the amorphous phase and looseness of chain packing …”

Interfacial Hydrogen Atom Transfer by nanohybrids based on Humic Acid Like Polycondensates

“…In this context, it has been demonstrated recently that grafting of gallic acid on SiO 2 nanoparticles [7] results in a hybrid material that is very efficiently as Hydrogen Atom Transfer agent [7]. The benefits of grafting a phenolic antioxidant molecule on a polymer-matrix have also been exemplified [22].…”

Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group

“…Meanwhile, evidence has suggested that saccharide derivatives containing amino groups were more excellent than natural saccharide as a scavenger of hydroxyl radicals [23]. Moreover, many reports have proposed that appropriate macromolecular systems, namely antioxidant-polymer conjugates, could combine the merits of several components, which retains the admirable biological activities of antioxidant molecules, possessing a higher stability and a slower degradation rate than the antioxidant molecules [24][25][26].…”