Chitosan Containing Nano Zn-Organic Framework: Synthesis, Characterization and Biological Activity

Gouda, Mohamed; Ibrahim, Hairul-Islam Mohamed; Negm, Amr

doi:10.3390/polym14071276

Cited by 4 publications

(1 citation statement)

References 53 publications

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“…A great number of slit pores can be seen on the MCS surface in the high-magnification SEM image as shown in Fig. 2 c. In addition to being a material with a high surface area, its porous structure may provide more adsorption sites and enhancing MCS's capacity to adsorb anionic dyes in sugar solutions 22 . Nearly spherical and hexagonal nanoparticles with an average diameter of about 40 nm are visible in the sample’s TEM image.…”

Section: Resultsmentioning

confidence: 98%

Bifunctional of Fe3O4@chitosan nanocomposite as a clarifying agent and cationic flocculant on different sugar solutions as a comprehensive semi industrial application

Dardeer,

Ibrahim,

Gad

et al. 2024

Sci Rep

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In the sugar industry, eliminating side impurities throughout the manufacturing process is the most significant obstacle to clarifying sugar solutions. Herein, magnetic chitosan (MCS) nanocomposite was Fabricated to be used as a biodegradable, environmentally friendly clarifying agent throughout the cane juice and sugar refining processes. Fe3O4 was synthesized using the coprecipitation procedure, and then MCS was combined using a cross-linking agent. Furthermore, 14.76 emu g−1 was the maximum saturation magnetization (Ms) value. Because MCS is magnetically saturated, it may be possible to employ an external magnetic field to separate the contaminant deposited on its surface. Additionally, zeta potential analysis showed outstanding findings for MCS with a maximum value of (+) 20.7 mV, with improvement in color removal % up to 44.8% using MCS with more than 24% in color removal % compared to the traditional clarification process. Moreover, utilizing MCS reduced turbidity from 167 to 1 IU. Overall, we determined that MCS nanocomposite exhibits considerable effectiveness in the clarifying process for different sugar solutions, performing as an eco-friendly bio-sorbent and flocculating material.

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Section: Resultsmentioning

confidence: 98%

Bifunctional of Fe3O4@chitosan nanocomposite as a clarifying agent and cationic flocculant on different sugar solutions as a comprehensive semi industrial application

Dardeer,

Ibrahim,

Gad

et al. 2024

Sci Rep

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Multifaced Antifungal Activity of Dialdehyde Chitosan Loaded with Zinc Metal-Organic Framework (Zn-MOF)

Kirui,

Madivoli,

Nzilu

et al. 2024

Waste Biomass Valor

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Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment

Choukaife¹,

Seyam²,

Alallam³

et al. 2022

IJN

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As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020 in both sexes and at all ages. The available anticancer therapies including chemotherapy, radiotherapy and anticancer drugs are all associated with limited therapeutic efficacy, adverse effects and low chances. This has urged to emerge several novel therapeutic agents as potential therapies for CRC including synthetic and natural materials. Orally administrable and targeted drug delivery systems are attractive strategies for CRC therapy as they minimize the side effects, enhance the efficacy of anticancer drugs. Nevertheless, oral drug delivery till today faces several challenges like poor drug solubility, stability, and permeability. Various oral nano-based approaches and targeted drug delivery systems have been developed recently, as a result of the ability of nanoparticles to control the release of the encapsulant, drug targeting and reduce the number of dosages administered. The unique physicochemical properties of chitosan polymer assist to overcome oral drug delivery barriers and target the colon tumour cells. Chitosan-based nanocarriers offered additional improvements by enhancing the stability, targeting and bioavailability of several anti-colorectal cancer agents. Modified chitosan derivatives also facilitated CRC targeting through strengthening the protection of encapsulant against acidic and enzyme degradation of gastrointestinal track (GIT). This review aims to provide an overview of CRC pathology, therapy and the barriers against oral drug delivery. It also emphasizes the role of nanotechnology in oral drug targeted delivery system and the growing interest towards chitosan and its derivatives. The present review summarizes the relevant works to date that have studied the potential applications of chitosan-based nanocarrier towards CRC treatment.

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Chitosan Containing Nano Zn-Organic Framework: Synthesis, Characterization and Biological Activity

Cited by 4 publications

References 53 publications

Bifunctional of Fe3O4@chitosan nanocomposite as a clarifying agent and cationic flocculant on different sugar solutions as a comprehensive semi industrial application

Bifunctional of Fe3O4@chitosan nanocomposite as a clarifying agent and cationic flocculant on different sugar solutions as a comprehensive semi industrial application

Multifaced Antifungal Activity of Dialdehyde Chitosan Loaded with Zinc Metal-Organic Framework (Zn-MOF)

Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment

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