Chitosan performance during Paralytic Shellfish Toxins (PST) depuration of Mytilus chilensis exposed to Alexandrium catenella

Tobke, Jésica L.; Giarratano, Erica; Ortíz, Alejandro; Garrido, Carla; Serra, Mônica da Costa; Gil, Mónica N.; Navarro, Jorge M.

doi:10.1016/j.toxicon.2021.03.008

Cited by 7 publications

(1 citation statement)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various strategies have been investigated for PST depuration in shellfish, involving chemical, biological, and physical procedures [9]. Among these, the application of adsorbents to eliminate PST appears to be promising, with different adsorbents already reported, such as chitin shell powder [10], clays [11,12], carrageenan [13], activated charcoal [14,15], and chitosan derivatives, either in the free form (chitosan) [16,17] or using carboxymethyl chitosan (CMC) [18].…”

Section: Introductionmentioning

confidence: 99%

Cation-Exchange Resin Applied to Paralytic Shellfish Toxins Depuration from Bivalves Exposed to Gymnodinium catenatum

Leal

Bombo

Amado

et al. 2023

Foods

View full text Add to dashboard Cite

The accumulation of marine biotoxins in shellfish and their consumption causes serious food safety problems, threatening human health and compromising the availability of protein-based food. It is thus urgent to develop methodologies for the detoxification of live bivalves, avoiding their economic and nutritional devaluation. In this context, we tested an adsorption mechanism of paralytic shellfish toxins (PST) based on a cation-exchange resin. The first studies using cultures of Gymnodinium catenatum (natural producers of PST) showed a decrease of about 80% in overall toxicity after 48 h. Interestingly, we found that the toxins are adsorbed differently, with toxins’ structural features playing a part in the adsorption capacity via steric hindrance, electronic effects, or the extent of positive charge density (e.g., dcSTX). The positive effect of the resin in accelerating PST clearance from live mussels (Mytilus edulis) is not evident when compared to resin-free clearance; nevertheless, relevant information could be gathered that will facilitate further in vivo studies. Several factors appear to be at play, namely the competition of natural substances (e.g., salts, organic matter) for the same binding sites, the blocking of pores due to interactions between molecules, and/or difficulties in resin absorption by mussels. Additionally, the present work revealed the ability of mussels to neutralize pH and proposes bioconversion reactions among the PST molecules.

show abstract