Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

Xiong, Yu; Cheng, Lei; Wang, Xiaoyi; Shen, Ye-Hua; Liu, Cong; Ren, Difeng

doi:10.1007/s11051-023-05672-y

Cited by 6 publications

(2 citation statements)

References 45 publications

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“…The FTIR spectra of the TPP-Chitosan and TPP-Chitosan-ZnO NPs are shown in Figure . A typical band at 3362 cm –1 can be attributed to the −OH stretching vibration, which overlaps the stretching band of −NH, making it a broad band, as previously observed. , The absorption bands centered around 1980, 1640, 1550, and 1375 cm –1 and present for both TPP-Chitosan and TPP-Chitosan-ZnO could correspond to symmetric and asymmetric CO stretching, respectively. , Besides, the peak at about 1050 cm –1 indicates that the phosphate moiety of TPP is connected to the amine group of chitosan based on electrostatic interaction, which agrees with a previous report . Following incorporation of ZnO NPs into TPP-Chitosan NPs, the peak at 1050 cm –1 was slightly shifted, suggesting a likely interaction of dissolved Zn ions with a −OH group in the TPP-Chitosan.…”

Section: Resultssupporting

confidence: 64%

“…43,45 Besides, the peak at about 1050 cm −1 indicates that the phosphate moiety of TPP is connected to the amine group of chitosan based on electrostatic interaction, which agrees with a previous report. 46 Following incorporation of ZnO NPs into TPP-Chitosan NPs, the peak at 1050 cm −1 was slightly shifted, suggesting a likely interaction of dissolved Zn ions with a −OH group in the TPP-Chitosan. Furthermore, two new absorption peaks at around 465 and 450 cm −1 were noticed, which correspond to the stretching mode of ZnO and align with observations from previous studies.…”

Section: Characterization Of Tpp-chitosan and Tpp-chitosan-zno Nanofe...mentioning

confidence: 99%

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Chitosan and Zinc Oxide Nanoparticle-Enhanced Tripolyphosphate Modulate Phosphorus Leaching in Soil

Dimkpa

Deng

Wang

et al. 2023

ACS Agric. Sci. Technol.

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Phosphorus (P) loss from agro-ecosystems impinges upon P use efficiency by plants and thereby constitutes both agronomic and environmental nuisances. Herein, we report on the potential for controlling P leaching loss and application in crop fertilization through repurposing and nano-functionalizing tripolyphosphate (TPP) as a sole P source. The developed TPP-Chitosan and TPP-Chitosan-ZnO nanofertilizers exhibited positive surface charges, 5.8 and 13.8 mV, and hydrodynamic sizes of 430 and 301 nm, respectively. In soil, nanoformulations of TPP-Chitosan and TPP-Chitosan-ZnO significantly reduced cumulative P leaching during 72 h, reaching 91 and 97% reductions, respectively, compared to a conventional fertilizer, monoammonium phosphate (MAP). Cumulative P leaching after 72 h from these nanofertilizers was, respectively, 84 and 95% lower than from TPP alone. TPP-Chitosan-ZnO was, overall, 65% more effective in reducing P leaching, compared to TPP-Chitosan. Relative to MAP, the wheat plant height was significantly increased by TPP-Chitosan-ZnO by 33.0%. Compared to MAP, TPP-Chitosan and TPP-Chitosan-ZnO slightly increased wheat grain yield by 21 and 30%, respectively. Notably, TPP-Chitosan-ZnO significantly decreased shoot P levels, by 35.5, 47, and 45%, compared to MAP, TPP, and TPP-Chitosan, respectively. Zn release over 72 h from TPP-Chitosan-ZnO was considerably lower, compared to a control, ZnO nanoparticles, and averaged, respectively, 34.7 and 0.065 mg/L, which was 534 times higher for the former. Grain Zn was significantly higher in the TPP-Chitosan treatment, relative to MAP. TPP-Chitosan also significantly mobilized the resident K, S, Mg, and Ca from soil into the plant, helping to improve the overall nutritional quality and supporting the role of chitosan in nutrient mobilization. Taken together, our data highlight the potential for repurposing a non-fertilizer P material, TPP, for agricultural and environmental applications and the effect of applying nanotechnology on such outcomes. Broadly speaking, the reduction in P loss is critical for controlling the eutrophication of water bodies due to nutrient overload and for sustaining the dwindling global P resources.

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Section: Resultssupporting

confidence: 64%

Section: Characterization Of Tpp-chitosan and Tpp-chitosan-zno Nanofe...mentioning

confidence: 99%

Chitosan and Zinc Oxide Nanoparticle-Enhanced Tripolyphosphate Modulate Phosphorus Leaching in Soil

Dimkpa

Deng

Wang

et al. 2023

ACS Agric. Sci. Technol.

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A comprehensive study on the application properties of different soft, hard, and functional monomers to polyacrylate emulsion and water‐based inks

Tian,

Li,

et al. 2024

J of Applied Polymer Sci

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The urge to protect the deteriorating ecosystem is compelling us to develop environmental‐friendly materials. In this paper, three different kinds of waterborne polyacrylate emulsions were synthesized with different hard, soft and hydroxyl‐containing functional monomers by semi‐continuous seed emulsion polymerization. Moreover, the influences of different monomers on the performances such as viscosity, adhesion, surface tension, particle size, stability, and contact angle were also investigated. Attractively, conclusions were deduced that with the growth of the monomer's alkyl chain length, the viscosity gradually increases and the surface tension gradually decreases. On the other hand, different functional monomers also have effect on the properties of the synthesized acrylic emulsions. Then the synthesized water‐based acrylic emulsions were used as binders for water‐based inks, the adhesion as well as initial dryness were tested and the recipe for water‐based ink with better performances was selected out. Our work maybe ignites a spark for the designation of acrylic emulsions for water‐based inks binders.

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Preparation and characterization of bovine serum albumin/chitosan composite nanoparticles for delivery of Antarctic krill peptide

Gao,

Luo,

et al. 2024

J Sci Food Agric

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BACKGROUNDAntarctic krill peptide (AKP) has gained considerable interest because of its multiple biological functions. However, its application may be limited by its poor stability and susceptibility to degradation. Encapsulation of AKP using a nanoparticle delivery system is an effective way to overcome these problems. In the present study, bovine serum albumin (BSA) and chitosan (CS) were used as delivery vehicles to encapsulate AKP.RESULTSThe results revealed that the particle size (83.3 ± 4.4–222.4 ± 32.7 nm) and zeta‐potential (35.1 ± 0.7–45.0 ± 2.7 mV) of nanoparticles (NPs) increased with the increasing content of BSA, but the polydispersity index decreased (1.000 ± 0.002 to 0.306 ± 0.011). Hydrogen bonding, hydrophobic and electrostatic interactions were the main forces to form BSA/CS‐AKP NPs. X‐ray diffraction revealed that AKP was encapsulated by BSA/CS. Scanning electron microscopy images exhibited that the NPs were spherical in shape, uniform in size and tightly bound. BSA/CS‐AKP NPs exhibited excellent stability in the pH range (2–5) and after 15 days of storage, and could hinder the release of AKP in simulated gastric environment and promote the release of AKP in simulated intestinal environment. After simulated digestion, the hypoglycemic activity of encapsulated AKP was better than that of unencapsulated AKP.CONCLUSIONOur results revealed that the BSA/CS showed great potential for protecting and delivering AKP. © 2024 Society of Chemical Industry.

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Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

Cited by 6 publications

References 45 publications

Chitosan and Zinc Oxide Nanoparticle-Enhanced Tripolyphosphate Modulate Phosphorus Leaching in Soil

Chitosan and Zinc Oxide Nanoparticle-Enhanced Tripolyphosphate Modulate Phosphorus Leaching in Soil

A comprehensive study on the application properties of different soft, hard, and functional monomers to polyacrylate emulsion and water‐based inks

Preparation and characterization of bovine serum albumin/chitosan composite nanoparticles for delivery of Antarctic krill peptide

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