Chloramphenicol assay by EMIT

Andrews, J. M.; Ashby, J. P.; Wise, R.

doi:10.1093/jac/21.5.682

Cited by 55 publications

(72 citation statements)

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“…Anti-bacterial and anti-fungal activities of the synthesized metal complexes were performed using well diffusion assay [29]. Bacterial (Escherichia coli, Staphylococcus aureus, Salmonelle paratyphi, Bacillus substilis) and fungal strains (Candida albicans, Aspergillus niger, Aspergillus fumigate) were used as test organisms in this study.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

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Synthesis, characterization, thermal behavior and antimicrobial activity of 3-methyl benzoate complexes of transition metal with hydrazine

Mohanapriya¹,

Muthukumaran²,

Vairam³

2016

Bull. Chem. Soc. Eth.

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ABSTRACT. Reaction of the ligands, 3-methyl benzoic acid (mbH) and hydrazine with transition metal ions form the complexes of formulae, [M(N2H4)2(mb)2].H2O where M = Co(II) and Zn(II) at pH = 5-6, [M(N2H4)n(mb)2].xH2O where M = Ni(II), n = 2, x = 0 at pH = 5 and M = Cd, n = 1, x = 1 at pH = 6. The same acid also forms metal carboxylates with zinc and copper of formula, [Zn(mb)2H2O].H2O at pH = 6 and [Cu(mb)2].H2O at pH = 5, respectively. The IR spectra of the complexes show that hydrazine is present as bridging bidentate ligand and the carboxylic acid as monodentate bridging carboxylate anion. The electronic spectra, magnetic moments and ESR spectral data suggest the coordination number. Thermal studies show that cobalt, zinc and nickel complexes containing hydrazine, and carboxylates of copper, zinc on their thermal decomposition form the corresponding metal oxides in nano size in the temperature range 755-815 °C. The antibacterial and antifungal activity show that both activities of the complexes are higher than that of the acid and among the complexes, cadmium compound shows more antimicrobial activity towards bacteria and fungi.

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Section: Antimicrobial Activitymentioning

confidence: 99%

“…The experiment was carried out with a blank under the same condition for each organism and by subtracting the diameter of inhibition zone of the blank from that obtained in each case. Anti-bacterial and anti-fungal activities are a mean of three replicates [29].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Synthesis, characterization, thermal behavior and antimicrobial activity of 3-methyl benzoate complexes of transition metal with hydrazine

Mohanapriya¹,

Muthukumaran²,

Vairam³

2016

Bull. Chem. Soc. Eth.

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“…Figure 4 (a) Effects of 3b (50～100 μmol/L) on E. coli viability and (b) concentration-killing curve of 3b [24] . 由表 Fc-CORM 释放至少两个 CO. 抗菌实验发现, Fc-CORM …”

Section: Fc-corm 的抑菌活性研究mentioning

confidence: 99%

Antibacterial Fischer Carbenoid CO-Releasing Molecules

Zhou¹,

Zhou²,

Tang³

et al. 2016

Chin. J. Org. Chem.

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CO releasing molecules (CORMs) of transition metal carbonyl complexes are emerging as a new interdisciplinary advance of inorganic chemistry, biological medicine and materials chemistry. In this paper, new ionic Fischer carbene carbonyl complexes were devised, in which Cr, Mo and W metals as metallic center carried five CO whilst the quaternary ammonium finely tuned the water solubility of Fc-CORMs. The myoglobin assays showed that one Fc-CORM released at least two molecules of carbon monoxide in well-controlled fashion under physiological conditions. The structure-releasing correlation revealed that the central metal was the key factor governing their carbon monoxide release behavior. The CO release rate of Fc-CORM-Mo (2a～2e) is quicker than Fc-CORM-Cr (1a～1e), much faster than Fc-CORM-W (3a～3e). The antibacterial activity test found that Fc-CORM (1b) with medium CO release rate effectively inhibited the growth and survival of Escherichia coli, with an minimal inhibitory concentration (MIC) value of 30 μmol/L. As for drug-resistant bacteria, Fc-CORM (2a～2e) and Fc-CORM (3a～3e) showed bactericidal activity. Mechanism study indicated that the antibacterial activity relied on the CO release rate of Fc-CORMs.

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“…MIC determination followed the protocol described by Andrews 28 . 10 mg/mL dilution of HEC m -g-P(IL) n s in iso-sensitest broth were prepared and 11 sequential 2-fold dilutions were made using the medium as diluent.…”

Section: Determination Of Minimum Inhibitory Concentration (Mic)mentioning

confidence: 99%

Preparation of an Antibacterial Poly(ionic liquid) Graft Copolymer of Hydroxyethyl Cellulose

et al. 2015

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Poly(ionic liquid)s (P(IL)s) of different degrees of polymerization (10, 50, and 100) were prepared via RAFT polymerization using an alkyne-terminated xanthate as transfer agent, with a monomer conversion of up to ∼80% and a Đ M of 1.5 for P(IL)100. Subsequently, P(IL) chains were coupled to 15N-labeled azido-functionalized hydroxyethyl cellulose (HEC), forming graft copolymers of HEC with different chain length and graft densities, which were characterized using (13C and 15N) CP-MAS NMR and FT-IR spectroscopies. The antibacterial activities of HEC-g-P(IL)s were tested against Escherichia coli and Staphylococcus aureus and were comparable to ampicillin, a well-known antibiotic, demonstrating efficient activity of the graft copolymers against bacteria. Moreover, HEC-g-P(IL)s were slightly more effective against E. coli than S. aureus. A decrease in graft density of P(IL)10 on the HEC backbone decreased the activity of the graft copolymers against both bacteria. These findings suggest that HEC-g-P(IL) could find applications as an antiseptic compound, for example, in paint formulation.

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Chloramphenicol assay by EMIT

Cited by 55 publications

References 0 publications

Synthesis, characterization, thermal behavior and antimicrobial activity of 3-methyl benzoate complexes of transition metal with hydrazine

Synthesis, characterization, thermal behavior and antimicrobial activity of 3-methyl benzoate complexes of transition metal with hydrazine

Antibacterial Fischer Carbenoid CO-Releasing Molecules

Preparation of an Antibacterial Poly(ionic liquid) Graft Copolymer of Hydroxyethyl Cellulose

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