Abstract:The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated chlorobenzene [
108‐90‐7
] to derive a maximum concentration at the workplace (MAK value), considering all toxicity endpoints. Adverse effects are a depression of the central nervous system in humans and histological alterations in liver and kidneys in rats. A 2‐generation reproduction study with chlorobenzene vapour in Sprague‐Dawley rats resulted in a NOAEC of 50 ml/m
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