Chlorhexidine is a highly effective topical broad-spectrum agent against Candida spp.

Salim, Nesreen A.; Moore, Caroline B.; Silikas, Nick; Satterthwaite, Julian D.; Rautemaa, Riina

doi:10.1016/j.ijantimicag.2012.08.014

Cited by 37 publications

(21 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Salim et al . compared, in vitro, the antifungal effect of chlorhexidine and fluconazole in 79 isolates of eight different species of oral Candida .…”

Section: Introductionmentioning

confidence: 99%

Use of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric patients

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Salim et al . compared, in vitro, the antifungal effect of chlorhexidine and fluconazole in 79 isolates of eight different species of oral Candida .…”

Section: Introductionmentioning

confidence: 99%

Use of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric patients

et al. 2017

View full text Add to dashboard Cite

show abstract

“…A probable explanation for the conflict results is that mouth rinses may contain alcohol that enhances significantly antimicrobial action of CHX, that is not present in CHX gel (Carvalhinho et al, ). Different methodologies using planktonic fungi cells (Ferguson, Hatton, & Gillespie, ; Salim, Moore, Silikas, Satterthwaite, & Rautemaa, ) presented antimicrobial action of CHX, but the results cannot be compared with this study, due to a matrix of exopolymeric substances present in biofilm, that protect cells and enhances resistance to drugs compared to their planktonic counterparts (Sardi et al, ).…”

Section: Discussionmentioning

confidence: 75%

Antimicrobial activity of intracanal medications against both Enterococcus faecalis and Candida albicans biofilm

Zancan

Calefi

Borges

et al. 2018

Microscopy Res & Technique

View full text Add to dashboard Cite

Enterococcus faecalis and Candida albicans have been associated with cases of secondary and persistent root canal infections, been resistant to calcium hydroxide. So, the evaluation of the susceptibility of these microorganisms biofilms to new drugs is an important practice for establishing the best drug and consequently success of treatment. For this, in vitro biofilm formation of E. faecalis and C. albicans was induced separately on blocks obtained from bovine teeth. After the period of specimen incubation for biofilm maturation, the samples were immersed in the pastes: 1 – calcium hydroxide (CH), 2 – chlorhexidine (C), 3 – ciprofloxacin (CP), 4 – metronidazole (MT), 5 – ketoconazole (KE), 6 – double antibiotic (DB), 7 – triple antibiotic (TA), 8 – ciprofloxacin + ketoconazole (CPKE); 9 – ciprofloxacin + metronidazole + ketoconazole (CPMTKE), 10 – metronidazole + ketoconazole (MTKE), and 11 – control (CO) for 7 days. Next, the specimens were live/dead stained for analysis by confocal microscopy. By means of the Bioimage program, the biovolume and percentage of live cells were measured. The data were statistically compared (p = .05). For the C. albicans biofilm, the best antimicrobial action was found for MTKE, CPKE, and MT groups. Whereas for E. faecalis biofilm, the lowest percentage of live bacteria was found in TA, DB, and CP groups; however, KE, CPKE, CPMTKE, and MTKE groups shown to be effective. The authors concluded calcium hydroxide paste and chlorhexidine was not effective for both biofilms. The MTKE and CPKE pastes presented effectiveness for both biofilms. TA and DB pastes were effective just in the E. faecalis biofilms.

show abstract

“…This evidence has been shown on microbiologic tests. (25,14,26,27,28) Type IV stone (gypsum) was used for pouring of tissue conditioner functional impression due to its ease of manipulation, affordability, appropriateness for impression material used and availability in various colors. (28) Our results revealed that the mean surface roughness (Ra, μm) of dental stone made from tissue conditioner had the highest values after immersion for 1hr.…”

Section: Discussionmentioning

confidence: 99%

The influence of different immersion time intervals and disinfection of tissue conditioner functional impression materials on the surface roughness of stone cast

Binmahfooz

2018

Egyptian Dental Journal

View full text Add to dashboard Cite

Tissue conditioners are used as a functional impression material, to re-condition the denturebearing mucosa abused by ill-fitting dentures and as a temporary lining material for immediate dentures. The immersion of tissue conditioners in disinfectant prior to pouring the impression can significantly affect the properties of dental stone depending on the duration of immersion. The present study aims to evaluate the effect of immersion time of tissue conditioner on the surface roughness of dental stone. Thirty specimens of tissue conditioner stone casts were prepared on cylindrical split aluminum with a lower hollow ring designed to receive the tissue conditioner and an upper ring adjusted to receive the stone mix. The thirty specimens of tissue conditioner were divided into 3 equal groups of 10 specimens according to the storage period (1hr, 24hrs and 48hrs). The three groups were subdivided into two subgroups: subgroup (a) 2% chlorhexidine (CHX) solution were sprayed on the surface of tissue conditioner specimens prior to pouring with dental stone materials while the other subgroup (b) specimens were poured with dental stone but without using (CHX) disinfection. The dental stone mixture was poured into molds and stored at room temperature for 60 minutes. The stone casts were then separated from the tissue conditioner and the surface roughness values of these dental stone casts was determined. Our results revealed a significant higher means values of surface roughness of groups (IIa and IIIa) when chlorhexidine was used compared to groups (IIb and IIIb). Comparison between subgroups (a and b) showed a statistical significance between (IIa and IIb) and (IIIa and IIIb). Based on the obtained results it can be concluded that the optimum time for using tissue conditioner as functional impression is from 24 to 48 hours after immersion. The use of 2% chlorhexidine solution disinfectant had adverse effect on surface roughness of dental stone.

show abstract

Chlorhexidine is a highly effective topical broad-spectrum agent against Candida spp.

Cited by 37 publications

References 27 publications

Use of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric patients

Use of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric patients

Antimicrobial activity of intracanal medications against both Enterococcus faecalis and Candida albicans biofilm

The influence of different immersion time intervals and disinfection of tissue conditioner functional impression materials on the surface roughness of stone cast

Contact Info

Product

Resources

About