2024
DOI: 10.1111/rda.14596
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Chlorogenic acid improves the development of porcine parthenogenetic embryos by regulating oxidative stress and ameliorating mitochondrial function

He‐Xuan Qu,
Yan‐Qiu Wang,
Yan‐Wei Dong
et al.

Abstract: Chlorogenic acid (CGA) is an effective phenolic antioxidant that can scavenge hydroxyl radicals and superoxide anions. Herein, the protective effects and mechanisms leading to CGA‐induced porcine parthenogenetic activation (PA) in early‐stage embryos were investigated. Our results showed that 50 μM CGA treatment during the in vitro culture (IVC) period significantly increased the cleavage and blastocyst formation rates and improved the blastocyst quality of porcine early‐stage embryos derived from PAs. Then, g… Show more

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